Survival after breast conservation vs mastectomy adjusted for comorbidity and socioeconomic status: A Swedish national 6-year follow-up of 48986 women

This cohort study used prospectively collected national data and included women diagnosed with primary invasive T1-2 N0-2 breast cancer. Patients underwent breast surgery in Sweden (2008-2017; n=48986 with median follow up of 6.28 years). Patients received BCS and radiotherapy (n=29367; 59.9%), mastectomy without radiotherapy (n=12413; 25.3%), or mastectomy with radiotherapy (n=7206; 14.7%). 5 year OS was 91.1% and BCSS was 96.3%. OS and BCSS were significantly worse after mastectomy without radiotherapy (HR 1.79 and HR 1.66 respectively) and mastectomy with radiotherapy (HR 1.24 and HR 1.26 respectively) than after BCS and radiotherapy. 

Classifications: Breast & Oncoplastic Surgery

Keywords: Breast Conserving Surgery Mastectomy Trials